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Pain and Neurogenic Inflammation - P.K. Moore, Susan Brain
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P.K. Moore, Susan Brain:

Pain and Neurogenic Inflammation - neues Buch

3, ISBN: 9783034887533

ID: 203179783034887533

Pain and inflammation are inextricably linked phenomena. The observation that chemical mediators with combined pro-inflammatory, algesic and/or hyperalgesic activity occur at the site of inflammation is fundamental not only to our present understanding of the inflammatory process but also to our attempts to devise clini- cally useful anti-inflammatory therapies. Over a hundred years ago it was recognised that primary sensory neurones play a crucially important "dual" role in inflammation. By aff Pain and inflammation are inextricably linked phenomena. The observation that chemical mediators with combined pro-inflammatory, algesic and/or hyperalgesic activity occur at the site of inflammation is fundamental not only to our present understanding of the inflammatory process but also to our attempts to devise clini- cally useful anti-inflammatory therapies. Over a hundred years ago it was recognised that primary sensory neurones play a crucially important "dual" role in inflammation. By affecting the transfer of infor- mation from peripheral nociceptors to the spinal cord, a subpopulation of sensory nerves {"pain fibres"} initiate algesia and hyperalgesia, whose sensations are then modified and fine-tuned in the central nervous system. Equally important is the release from the peripheral terminals of sensory neurones of neuropeptides, the acute effects of which are observed as changes in microvascular tone and perme- ability leading to neurogenic inflammation. Over the last decade it has become increasingly clear that this view of the func- tion of sensory nerves is somewhat over-simplified. For example, the mechanisms underlying hyperalgesia may, in certain circumstances, be mimicked in other condi- tions such as the hypersensivity associated with asthma. Furthermore, it has become increasingly evident that over a longer time period the release of neuropeptides from peripheral sensory nerve endings may also have modulating effects on inmune cells and that this may be relevant to chronic inflammatory disease and possibly also to inflammatory hyperalgesia. Medical, Health & Well Being, Pain and Neurogenic Inflammation~~ P.K. Moore, Susan Brain~~Medical~~Health & Well Being~~9783034887533, en, Pain and Neurogenic Inflammation, P.K. Moore, Susan Brain, 9783034887533, Birkhäuser, 03/11/2013, , , , Birkhäuser, 03/11/2013

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Pain and Neurogenic Inflammation - P.K. Moore, Susan Brain
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)

P.K. Moore, Susan Brain:

Pain and Neurogenic Inflammation - neues Buch

3, ISBN: 9783034887533

ID: 203179783034887533

Pain and Neurogenic Inflammation Adult, Health & Well Being, Pain and Neurogenic Inflammation~~ P.K. Moore, Susan Brain~~Adult~~Health & Well Being~~9783034887533, en, Pain and Neurogenic Inflammation, P.K. Moore, Susan Brain, 9783034887533, Birkhäuser, 03/11/2013, , , , Birkhäuser, 03/11/2013

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E-Book zum download Versandkosten: EUR 0.00
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(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.

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Details zum Buch
Pain and Neurogenic Inflammation
Autor:

P.K. Moore, Susan Brain

Titel:

Pain and Neurogenic Inflammation

ISBN-Nummer:

9783034887533

Detailangaben zum Buch - Pain and Neurogenic Inflammation


EAN (ISBN-13): 9783034887533
Erscheinungsjahr: 3
Herausgeber: Birkhäuser

Buch in der Datenbank seit 30.12.2014 23:22:51
Buch zuletzt gefunden am 07.09.2016 19:28:47
ISBN/EAN: 9783034887533

ISBN - alternative Schreibweisen:
978-3-0348-8753-3

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