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CD4 T Helper Cells in ACAID and Corneal Immune Privilege - Khrishen Cunnusamy
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Khrishen Cunnusamy:
CD4 T Helper Cells in ACAID and Corneal Immune Privilege - Taschenbuch

ISBN: 9783847326410

[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], Neuware - Corneal transplantation is the oldest and most common form of solid organ transplantation. In uncomplicated first-time cases, corneal allografts enjoy a success rate of up to 90% even though the transplants are performed without HLA matching or the use of systemic immunosuppressive drugs. Yet, every year in the United States, nearly 8000 patients reject their transplanted corneas at a cost of a quarter of a billion dollars. In order to better understand the immune mechanisms underlying graft failure, my research examined the role of CD4+ Thelper lymphocytes in the process, notably the recently described Thelper 17 subset. Surprisingly, blockade of the effector CD4+ Thelper subsets, by depletion of their inflammatory cytokines, exacerbated corneal allograft rejection in a murine model of keratoplasty. Our investigations uncover novel protective roles for the cytokines IL-17A and IFN- , and describe how their interaction with T regulatory cells is required for anterior chamber associated immune deviation and corneal immune privilege., DE, [SC: 0.00], Neuware, gewerbliches Angebot, 220x150x9 mm, 156, [GW: 249g], PayPal, offene Rechnung, Banküberweisung, sofortueberweisung.de, Interntationaler Versand

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CD4 T Helper Cells in ACAID and Corneal Immune Privilege : A perspective from IL-17A - Khrishen Cunnusamy
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Khrishen Cunnusamy:
CD4 T Helper Cells in ACAID and Corneal Immune Privilege : A perspective from IL-17A - Taschenbuch

2011, ISBN: 3847326414

ID: 22506659670

[EAN: 9783847326410], Neubuch, [PU: LAP Lambert Academic Publishing Dez 2011], This item is printed on demand - Print on Demand Neuware - Corneal transplantation is the oldest and most common form of solid organ transplantation. In uncomplicated first-time cases, corneal allografts enjoy a success rate of up to 90% even though the transplants are performed without HLA matching or the use of systemic immunosuppressive drugs. Yet, every year in the United States, nearly 8000 patients reject their transplanted corneas at a cost of a quarter of a billion dollars. In order to better understand the immune mechanisms underlying graft failure, my research examined the role of CD4+ Thelper lymphocytes in the process, notably the recently described Thelper 17 subset. Surprisingly, blockade of the effector CD4+ Thelper subsets, by depletion of their inflammatory cytokines, exacerbated corneal allograft rejection in a murine model of keratoplasty. Our investigations uncover novel protective roles for the cytokines IL-17A and IFN- , and describe how their interaction with T regulatory cells is required for anterior chamber associated immune deviation and corneal immune privilege. 156 pp. Englisch

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CD4 T Helper Cells in ACAID and Corneal Immune Privilege - Khrishen Cunnusamy
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Khrishen Cunnusamy:
CD4 T Helper Cells in ACAID and Corneal Immune Privilege - Taschenbuch

2011, ISBN: 3847326414

ID: 22506672008

[EAN: 9783847326410], Neubuch, [PU: LAP Lambert Academic Publishing Dez 2011], Neuware - Corneal transplantation is the oldest and most common form of solid organ transplantation. In uncomplicated first-time cases, corneal allografts enjoy a success rate of up to 90% even though the transplants are performed without HLA matching or the use of systemic immunosuppressive drugs. Yet, every year in the United States, nearly 8000 patients reject their transplanted corneas at a cost of a quarter of a billion dollars. In order to better understand the immune mechanisms underlying graft failure, my research examined the role of CD4+ Thelper lymphocytes in the process, notably the recently described Thelper 17 subset. Surprisingly, blockade of the effector CD4+ Thelper subsets, by depletion of their inflammatory cytokines, exacerbated corneal allograft rejection in a murine model of keratoplasty. Our investigations uncover novel protective roles for the cytokines IL-17A and IFN- , and describe how their interaction with T regulatory cells is required for anterior chamber associated immune deviation and corneal immune privilege. 156 pp. Englisch

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CD4 T Helper Cells in ACAID and Corneal Immune Privilege als Buch von Khrishen Cunnusamy - Khrishen Cunnusamy
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CD4 T Helper Cells in ACAID and Corneal Immune Privilege als Buch von Khrishen Cunnusamy - gebunden oder broschiert

ISBN: 9783847326410

ID: 696666817

CD4 T Helper Cells in ACAID and Corneal Immune Privilege:A perspective from IL-17A Khrishen Cunnusamy CD4 T Helper Cells in ACAID and Corneal Immune Privilege:A perspective from IL-17A Khrishen Cunnusamy Bücher > Wissenschaft > Medizin, LAP Lambert Academic Publishing

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Cd4 T Helper Cells in Acaid and Corneal Immune Privilege - Khrishen Cunnusamy
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Cd4 T Helper Cells in Acaid and Corneal Immune Privilege - neues Buch

2011, ISBN: 3847326414

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[EAN: 9783847326410], Neubuch, [PU: LAP Lambert Academic Publishing], New Book. Delivered from our UK warehouse in 3 to 5 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000

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Detailangaben zum Buch - CD4 T Helper Cells in ACAID and Corneal Immune Privilege


EAN (ISBN-13): 9783847326410
ISBN (ISBN-10): 3847326414
Gebundene Ausgabe
Taschenbuch
Erscheinungsjahr: 2016
Herausgeber: LAP Lambert Academic Publishing

Buch in der Datenbank seit 14.01.2007 21:29:37
Buch zuletzt gefunden am 11.08.2017 08:17:30
ISBN/EAN: 3847326414

ISBN - alternative Schreibweisen:
3-8473-2641-4, 978-3-8473-2641-0


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