2008, ISBN: 0470122382
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2008, ISBN: 9780470122389
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2008, ISBN: 0470122382
[EAN: 9780470122389], Neubuch, [PU: Wiley-Interscience], Medical|Immunology, Medical|Pharmacology, Brand New, Unread Copy in Perfect Condition. A+ Customer Service! Summary: Preface.Contr… Mehr…
Herzyk, Danuta J.; Bussiere, Jeanine L.:
Immunotoxicology Strategies for Pharmaceutical Safety Assessment - neues BuchISBN: 9780470122389
An important reference which provides an overview of the current and recently introduced methodologies for testing the immunotoxic risks in drug candidates Helps readers understand the … Mehr…
2008, ISBN: 9780470122389
Hardcover, Buch, [PU: John Wiley & Sons Inc]
2008, ISBN: 9780470122389
Hardcover, Buch, [PU: Wiley-Blackwell]
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Detailangaben zum Buch - Immunotoxicology Strategies for Pharmaceutical Safety Assessment
EAN (ISBN-13): 9780470122389
ISBN (ISBN-10): 0470122382
Gebundene Ausgabe
Erscheinungsjahr: 2008
Herausgeber: John Wiley & Sons Inc
402 Seiten
Gewicht: 0,748 kg
Sprache: eng/Englisch
Buch in der Datenbank seit 2007-04-27T09:43:51+02:00 (Berlin)
Detailseite zuletzt geändert am 2021-12-04T09:09:00+01:00 (Berlin)
ISBN/EAN: 9780470122389
ISBN - alternative Schreibweisen:
0-470-12238-2, 978-0-470-12238-9
Alternative Schreibweisen und verwandte Suchbegriffe:
Autor des Buches: buss, bussi, jean bussiere
Titel des Buches: safety
Daten vom Verlag:
Autor/in: Danuta J. Herzyk; Jeanine L. Bussiere
Titel: Immunotoxicology Strategies for Pharmaceutical Safety Assessment
Verlag: John Wiley & Sons
432 Seiten
Erscheinungsjahr: 2008-09-12
Gewicht: 0,737 kg
Sprache: Englisch
165,00 € (DE)
No longer receiving updates
164mm x 239mm x 26mm
BB; Hardcover, Softcover / Chemie; Medizinische Chemie, Pharmazeutische Chemie; Chemie; Chemistry; Drug Discovery & Development; Immunologie; Immunology; Medical Science; Medizin; Pharmazeutische Chemie; Toxicology; Toxikologie; Wirkstoffforschung u. -entwicklung; Wirkstoffforschung u. -entwicklung; Toxikologie; Immunologie
Introduction to Immunotoxicology (Jack H. Dean). Chapter 1: Current Regulatory Expectations for Immunotoxicity Evaluation of Pharmaceuticals (Kenneth L. Hastings). Chapter 2: Weight of Evidence Review: A New Strategy in Immunotoxicology. 2.1. Clinical Pathology as Crucial Insight into Immunotoxicity Testing (Ellen Evans). 2.2. Histomorphology of the Immune System: A Basic Step in Assessing Immunotoxicity (Patrick Haley). 2.3. Need for Specialized Immunotoxicity Tests (Kazuchi Nakamura). 2.4. Specific Drug-Induced Immunotoxicity: Immune-Mediated Hemolytic Anemia (Raj Krishnaraj). Chapter 3: Nonclinical Core Immunotoxicity Testing in Drug Development. 3.1. Evaluation of Immunosuppression Potential by Immune Function Tests. 3.2. Evaluation of Drug Effects on Immune Cell Phenotypes (Laurie Iciek). Chapter 4: Extended Immunotoxicology Assessment: Ex Vivo Models. 4.1. Functional Cellular Responses and Cytokine Profiles (Elizabeth R. Gore). 4.2. Application of Flow Cytometry in Drug Development (Padma Narayanan, Nianyu Li, and Peter J. Bugelski). Chapter 5: Extended Immunotoxicology Assessment: In Vivo Models. 5.1. Animal Models of Host Resistance (Gary R. Burleson and Florence G. Burleson). 5.2. Approaches to Evaluation of Autoimmunity (Danuta J. Herzyk). Chapter 6: Immunotoxicity Testing in Biopharmaceutical Development. 6.1. Differentiation between Desired Immunomodulation and Potential Immunotoxicity (Jeanine L. Bussiere and Barbara Mounho). 6.2. Relevant Immune Tests across Different Species and Surrogate Models (Jeanine L. Bussiere). 6.3. Anti-Drug Antibody Responses in Preclinical Studies and Their Implications (Barbara Mounho). Chapter 7: Development of Vaccines. 7.1. Pharmacological Immunogenicity and Adverse Responses to Vaccines (Mary Kate Hart, Mark Bolanowski and Robert V. House). 7.2. Immunotoxicological Concerns for Vaccines and Adjuvants (Catherine Kaplanski, Jose Lebron, Jayanthi Wolf and Brian Ledwith). Chapter 8: Testing for Drug Hypersensitivity. 8.1. Systemic Hypersensitivity (Raymond Pieters). 8.2. Nonclinical Models to Assess Respiratory Hypersensitivity Potential (Curtis C. Maier). Chapter 9: Testing for Developmental Immunotoxicity. 9.1. Developmental Immunotoxicity in Rodents (Rodney R. Dietert and Leigh Ann Burns-Naas). 9.2. Developmental immunotoxicity in Non-Human Primates (Pauline L. Martin and Eberhard Buse). Chapter 10: New Methods in Assessing Immunomodulation, Immunotoxicity and Immunogenicity. 10.1. Alternative Animal Models for Immunomodulation and Immunotoxicity (Peter J. Bugelski). 10.2 Animal Models for Preclinical Comparative Immunogenicity Testing (Daniel Wierda). 10.3. T-Cell Epitopes and Minimization of Immunogenicity (Harald Kropshoffer and Thomas Singer). Chapter 11: Bridging Immunotoxicology to Clinical Drug Development (Ian Gourley and Jacques Descotes).Weitere, andere Bücher, die diesem Buch sehr ähnlich sein könnten:
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9780470386378 Immunotoxicology Strategies for Pharmaceutical Safety Assessment (Jeanine L. Bussiere; Danuta J. Herzyk)
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