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Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - Lena Daumann
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Lena Daumann:
Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - neues Buch

ISBN: 9783319066295

ID: 9783319066295

Lena Daumanns`s thesis describes structural and functional studies of the enzyme Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. It also examines the properties of small mimics of this enzyme and related binuclear metallohydrolases such as the metallo-ß-lactamases to enhance our understanding of hydrolytic cleavage of important substrates like phosphoesters and ß-lactams. Overall, this project has led to a better understanding of the metal ion binding and active site structural features of the enzyme GpdQ. Daumann describes how she successfully immobilized phosphoesterase and related biomimetics on solid supports for potential applications in the area of bioremediation of organophosphate pesticides. Analysis shows that both the enzyme and biomimetics can be stored on the solid support without loss of activity. Furthermore, the author specroscopically and mechanistically characterized a number of Zn(II), Cd(II) and Co(II) complexes, some of which are among the most active biomimetics towards organophosphates reported to date. This thesis makes excellent reading for non-specialists because each chapter includes a short introduction section. Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes: Lena Daumanns`s thesis describes structural and functional studies of the enzyme Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes. It also examines the properties of small mimics of this enzyme and related binuclear metallohydrolases such as the metallo-ß-lactamases to enhance our understanding of hydrolytic cleavage of important substrates like phosphoesters and ß-lactams. Overall, this project has led to a better understanding of the metal ion binding and active site structural features of the enzyme GpdQ. Daumann describes how she successfully immobilized phosphoesterase and related biomimetics on solid supports for potential applications in the area of bioremediation of organophosphate pesticides. Analysis shows that both the enzyme and biomimetics can be stored on the solid support without loss of activity. Furthermore, the author specroscopically and mechanistically characterized a number of Zn(II), Cd(II) and Co(II) complexes, some of which are among the most active biomimetics towards organophosphates reported to date. This thesis makes excellent reading for non-specialists because each chapter includes a short introduction section. Enzymology Phosphoesterase Enzymes Dinuclear Cobalt Complexes Magnetism Biomimetic Complex Antibiotic Resistance Biochemical Engineering Metallo-beta-lactamase Bioinspired Hydrolysis Magnetic Circular Dichrosim Spectroscopy/Spectrometry Organoph, Springer International Publishing

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Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - Daumann, Lena
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Daumann, Lena:
Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - neues Buch

2014, ISBN: 3319066293

ID: 9783319066295

In englischer Sprache. Verlag: Springer International Publishing, Introduction.- Experimental.- Understanding the Overall Structure of GpdQ and Metal Binding.- Structural and Mechanistic Studies of Zn(II) Complexes as Phosphoesterase Models.- Mechanistic Studies of Cd(II) Complexes as Phosphoesterase and Metallo-?-lactamase Models.- Spectroscopic and Mechanistic Studies of Co(II) Phosphoesterase and Metallo-?-lactamase Biomimetics.- Asymmetric Zn(II) Complexes as Structural and Functional Models for GpdQ.- Immobilization of GpdQ and Related Models for Bioremedial Applications.- Conclusion and Outlook. PC-PDF, 239 Seiten, XXI Seiten, 239 Seiten, [GR: 9675 - Nonbooks, PBS / Biologie/Biochemie, Biophysik], [SW: - Biochemie ], [Ausgabe: 2014][PU:Springer International Publishing]

Neues Buch Libreka.de
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Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - Lena Josefine Daumann
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Lena Josefine Daumann:
Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - neues Buch

ISBN: 9783319066295

ID: 9783319066295

Chemistry; Biochemical Engineering; Enzymology; Spectroscopy/Spectrometry Antibiotic Resistance, Bioinspired Hydrolysis, Biomimetic Complex, Dinuclear Cobalt Complexes Magnetism, Magnetic Circular Dichrosim, Metallo-beta-lactamase, Organophosphate Pesticide Bioremediation, Phosphoesterase Enzymes Books eBook, Springer Science+Business Media

Neues Buch Springer.com
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Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - Lena Josefine Daumann
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Lena Josefine Daumann:
Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - neues Buch

2014, ISBN: 9783319066295

ID: 30242494

2014, eBook Download (PDF), eBooks, [PU: Springer International Publishing]

Neues Buch Lehmanns.de
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Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - Lena Daumann
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Lena Daumann:
Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes - Erstausgabe

2014, ISBN: 9783319066295

ID: 30242494

[ED: 1], Auflage, eBook Download (PDF), eBooks, [PU: Springer-Verlag]

Neues Buch Lehmanns.de
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