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Humanized Mice (Current Topics in Microbiology and Immunology) - Tatsuji Nomura, Takeshi Watanabe, Sonoko Habu
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Tatsuji Nomura, Takeshi Watanabe, Sonoko Habu:
Humanized Mice (Current Topics in Microbiology and Immunology) - gebunden oder broschiert

ISBN: 3540756469

[SR: 6573206], Hardcover, [EAN: 9783540756460], Springer, Springer, Book, [PU: Springer], Springer, The term humanized mouse in this text refers to a mouse in which human tissues and cells have been transplanted and show the same biological function as they do in the human body. That is, the physiological properties and functions of tra- planted human tissues and cells can be analyzed in the mouse instead of using a living human body. It should therefore be possible to study the pathophysiology and treatment of human diseases in mice with good reproducibility. Thus, the hum- ized mouse can be used as a potent tool in both basic and clinical research in the future. The development of appropriate immunodeficient mice has been indispensable in the creation of the humanized mouse, which has been achieved through many years of efforts by several laboratories. The first stage on the road to the humanized mouse was the report on nude mice by Isaacson and Cattanach in 1962. Thereafter, nude mice were studied in detail by Falanagan and, in 1968, Pantelouris found that these mice have no thymus gland, which suggested that the mice lack transplan- tion immunity against xenografts such as human hematopoietic stem cells. At the Nude Mouse Workshops (organized by Regard, Povlsen, Nomura and colleagues) that were held nine times between 1972 and 1997, the possibility of creating a humanized mouse using nude mice was extensively examined. The results, however, showed that certain human cancers can be engrafted in nude mice, but unfortunately engraftment of normal human tissue was almost impossible., 720874, Anatomy, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 13499, Mammals, 13474, Animals, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 13511, Biochemistry, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 172406, Microbiology, 226688, Biology, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 13535, Genetics, 13824, Evolution, 75, Science & Math, 1000, Subjects, 283155, Books, 227192, Immunology, 227191, Basic Sciences, 173514, Medical Books, 1000, Subjects, 283155, Books, 227603, Physiology, 227191, Basic Sciences, 173514, Medical Books, 1000, Subjects, 283155, Books, 689711011, Biochemistry, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 689713011, Genetics, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 689715011, Immunology, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 689722011, Physiology, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 491704, Anatomy & Physiology, 491702, Biology & Life Sciences, 468216, Science & Mathematics, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books

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Humanized Mice (Current Topics in Microbiology and Immunology) - Tatsuji Nomura, Takeshi Watanabe, Sonoko Habu
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Tatsuji Nomura, Takeshi Watanabe, Sonoko Habu:
Humanized Mice (Current Topics in Microbiology and Immunology) - gebunden oder broschiert

ISBN: 3540756469

[SR: 6573206], Hardcover, [EAN: 9783540756460], Springer, Springer, Book, [PU: Springer], Springer, The term humanized mouse in this text refers to a mouse in which human tissues and cells have been transplanted and show the same biological function as they do in the human body. That is, the physiological properties and functions of tra- planted human tissues and cells can be analyzed in the mouse instead of using a living human body. It should therefore be possible to study the pathophysiology and treatment of human diseases in mice with good reproducibility. Thus, the hum- ized mouse can be used as a potent tool in both basic and clinical research in the future. The development of appropriate immunodeficient mice has been indispensable in the creation of the humanized mouse, which has been achieved through many years of efforts by several laboratories. The first stage on the road to the humanized mouse was the report on nude mice by Isaacson and Cattanach in 1962. Thereafter, nude mice were studied in detail by Falanagan and, in 1968, Pantelouris found that these mice have no thymus gland, which suggested that the mice lack transplan- tion immunity against xenografts such as human hematopoietic stem cells. At the Nude Mouse Workshops (organized by Regard, Povlsen, Nomura and colleagues) that were held nine times between 1972 and 1997, the possibility of creating a humanized mouse using nude mice was extensively examined. The results, however, showed that certain human cancers can be engrafted in nude mice, but unfortunately engraftment of normal human tissue was almost impossible., 720874, Anatomy, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 13499, Mammals, 13474, Animals, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 13511, Biochemistry, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 172406, Microbiology, 226688, Biology, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 13535, Genetics, 13824, Evolution, 75, Science & Math, 1000, Subjects, 283155, Books, 227192, Immunology, 227191, Basic Sciences, 173514, Medical Books, 1000, Subjects, 283155, Books, 227603, Physiology, 227191, Basic Sciences, 173514, Medical Books, 1000, Subjects, 283155, Books, 689711011, Biochemistry, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 689713011, Genetics, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 689715011, Immunology, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 689722011, Physiology, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 491704, Anatomy & Physiology, 491702, Biology & Life Sciences, 468216, Science & Mathematics, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books

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Humanized Mice 1st Edition - Tatsuji Nomura
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Humanized Mice 1st Edition Author :Tatsuji Nomura 9783540756460 3540756469, [PU: Springer, Berlin/Heidelberg]

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Details zum Buch
Humanized Mice

PBasic Concept of Development and Practical Application of Animal Models for Human Diseases.- Humanized SCID mouse models for biomedical research.- NOD/Shi-scid IL2 rgSUPnull/SUP (NOG) mice more appropriate for a humanized mouse model.- Humanizing Bone Marrow in Immune Dificient Mice.- The differentiative and regenerative properties of human hematopoietic stem/progenitor cells in the NOD-SCID/IL2rgSUPnull/SUPmice.- Antigen specific antibody production of human B cells in NOG mice reconstituted with human immune system.- Humanized Immune System (HIS) mice as a tool to study human NK cell development.- Human T cell development and HIV infection in Human Hemato-Lymphoid System Mice.- Humanized mice for human retrovirus infection.- Functional and Phenotypic Characterization of the Humanized BLT Mouse.- Novel metastasis models of human cancer in NOG mice.- In vivo imaging in humanized mice.- Subject index./P

Detailangaben zum Buch - Humanized Mice


EAN (ISBN-13): 9783540756460
ISBN (ISBN-10): 3540756469
Gebundene Ausgabe
Erscheinungsjahr: 2008
Herausgeber: Springer-Verlag GmbH
202 Seiten
Gewicht: 0,537 kg
Sprache: eng/Englisch

Buch in der Datenbank seit 24.05.2008 09:59:53
Buch zuletzt gefunden am 11.10.2017 09:22:23
ISBN/EAN: 9783540756460

ISBN - alternative Schreibweisen:
3-540-75646-9, 978-3-540-75646-0


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