ISBN: 9783642090059

Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial du… Mehr…

Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial during DNA replication in vegetatively growing cells. It plays a critical role in preserving the integrity of the genome by mediating the repair of DNA damage, which can occur during normal cellular metabolism as a result of oxidative stress, transcription, replication fork stalling or breakdown, or after the exposure to DNA damaging agents. Until recently, much of our knowledge on the mechanisms of genetic recombination has come from studies of prokaryotic and simple eukaryotic fungal systems. However, these studies have now been significantly extended to mammals, such that a comparative picture of the general factors and mechanisms of genetic recombination is beginning to emerge. Detailed genetic and biochemical studies have led to the isolation and characterization of many of the recombination-repair proteins in E. coli and S. cerevisiae, which in turn has led to the identification of homologues in human cells. The link between recombination defects and recombination proteins in a number of tumors as well as in human hereditary syndromes makes genetic recombination a cellular process of key importance not only in basic biology but also in biomedical studies. New Textbooks>Trade Paperback>Science>Biology>Biology, Springer Berlin Heidelberg Core >1 >T<

ISBN: 9783642090059

Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial du… Mehr…

Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial during DNA replication in vegetatively growing cells. It plays a critical role in preserving the integrity of the genome by mediating the repair of DNA damage, which can occur during normal cellular metabolism as a result of oxidative stress, transcription, replication fork stalling or breakdown, or after the exposure to DNA damaging agents. Until recently, much of our knowledge on the mechanisms of genetic recombination has come from studies of prokaryotic and simple eukaryotic fungal systems. However, these studies have now been significantly extended to mammals, such that a comparative picture of the general factors and mechanisms of genetic recombination is beginning to emerge. Detailed genetic and biochemical studies have led to the isolation and characterization of many of the recombination-repair proteins in E. coli and S. cerevisiae, which in turn has led to the identification of homologues in human cells. The link between recombination defects and recombination proteins in a number of tumors as well as in human hereditary syndromes makes genetic recombination a cellular process of key importance not only in basic biology but also in biomedical studies., Springer<

2010, ISBN: 9783642090059

Taschenbuch, Gebundene Ausgabe

gewerbliches Angebot, [SC: 0.00], Neuware, [PU: Springer], 548, [GW: 820g], [ED: Taschenbuch], Softcover reprint of hardcover 1st edition 2007, DE, This book covers one of the most import… Mehr…

gewerbliches Angebot, [SC: 0.00], Neuware, [PU: Springer], 548, [GW: 820g], [ED: Taschenbuch], Softcover reprint of hardcover 1st edition 2007, DE, This book covers one of the most important topics in modern biology: recombination. Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial during DNA replication in vegetatively growing cells. It plays a critical role in preserving the integrity of the genome by mediating the repair of DNA damage which can occur during normal cellular metabolism as a result of oxidative stress, transcription, replication fork stalling or breakdown, or after the exposure to DNA damaging agents. The book summarizes all existing views on the topic and puts them into context. It contains in-depth and up-to-date analysis of the chapter topics, written by international experts., Banküberweisung, PayPal, [CT: Sonstiges / Sonstiges]<

2010, ISBN: 9783642090059

Editor: Aguilera, Andrés, Editor: Rothstein, Rodney, Springer, Paperback, Auflage: Softcover reprint of hardcover 1st ed. 2007, 548 Seiten, Publiziert: 2010-11-19T00:00:01Z, Produktgruppe… Mehr…

Editor: Aguilera, Andrés, Editor: Rothstein, Rodney, Springer, Paperback, Auflage: Softcover reprint of hardcover 1st ed. 2007, 548 Seiten, Publiziert: 2010-11-19T00:00:01Z, Produktgruppe: Book, Hersteller-Nr.: 40 black & white illustrations, 30 colou, 0.82 kg, Biochemistry, Biological Sciences, Science & Math, Subjects, Books, Cell Biology, Microbiology, Molecular Biology, Botany, Trees, Plants, Zoology, Genetics, Evolution, Biology & Life Sciences, Science & Mathematics, New, Used & Rental Textbooks, Specialty Boutique, Holiday Books, 34875086-8a6a-4dfe-b095-4d85fb30b3ba_1601, 34875086-8a6a-4dfe-b095-4d85fb30b3ba_0, Special Features Stores, Arborist Merchandising Root, Format: Illustrated, Springer, 2010<

ISBN: 9783642090059

This work offers a fascinating insight into a crucial genetic process. Recombination is, quite simply, one of the most important topics in contemporary biology. This book is a totally com… Mehr…

This work offers a fascinating insight into a crucial genetic process. Recombination is, quite simply, one of the most important topics in contemporary biology. This book is a totally comprehensive treatment of the subject, summarizing all existing views on the topic and at the same time putting them into context. It provides in-depth and up-to-date analysis of the chapter topics, and has been written by international experts in the field. New Textbooks>Trade Paperback>Science>Biology>Biology, Springer Berlin Heidelberg Core >1 >T<