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High-Risk Human Papillomavirus and Cervical Carcinoma: A Study on Human Papillomavirus: High-Risk E6, p53 and p16 Proteins Expression and Their Role in Cervical Carcinogenesis - Arwa Al-Shuwaikh
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Arwa Al-Shuwaikh:
High-Risk Human Papillomavirus and Cervical Carcinoma: A Study on Human Papillomavirus: High-Risk E6, p53 and p16 Proteins Expression and Their Role in Cervical Carcinogenesis - Taschenbuch

2013, ISBN: 3659281050

Paperback, [EAN: 9783659281051], LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Book, [PU: LAP LAMBERT Academic Publishing], 2013-03-22, LAP LAMBERT Academic Publishing, Cervical cancer is one of the most frequent diseases in women,it is comprises approximately 12% of all cancer in women worldwide and the second most common type, after breast cancer, with about 200,000 deaths annually and 500,000 new cases per annum. Persistent infection with one or more carcinogenic types of human papillomavirus (HPV) is an important etiologic factor in the development of cervical intraepithelial neoplasia and the progression to cervical cancer. HPV DNA has been detected in up to 99.7% of invasive cervical cancers worldwide.The carcinogenic effect of the "high-risk" HPVs, as defined by their documented association with invasive carcinomas, is thought to be mediated by two viral oncoprotein, E6 and E7, through their action of inactivating the function of two important cellular tumor suppressor, p53 and pRb. It has been demonstrated that the E6 oncoprotein interacts with p53 to promote its degradation, whereas the E7 oncoprotein form complex with Rb, leading to its functional inactivation as well as accelerated degradation. These synergistic effects result in a deregulated cell cycle control and are thus believed to be critically important in HPV-induced carcinogene, 172406, Microbiology, 226688, Biology, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books

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High-Risk Human Papillomavirus and Cervical Carcinoma: A Study on Human Papillomavirus: High-Risk E6, p53 and p16 Proteins Expression and Their Role in Cervical Carcinogenesis - Arwa Al-Shuwaikh
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Arwa Al-Shuwaikh:
High-Risk Human Papillomavirus and Cervical Carcinoma: A Study on Human Papillomavirus: High-Risk E6, p53 and p16 Proteins Expression and Their Role in Cervical Carcinogenesis - Taschenbuch

2013, ISBN: 3659281050

Paperback, [EAN: 9783659281051], LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Book, [PU: LAP LAMBERT Academic Publishing], 2013-03-22, LAP LAMBERT Academic Publishing, Cervical cancer is one of the most frequent diseases in women,it is comprises approximately 12% of all cancer in women worldwide and the second most common type, after breast cancer, with about 200,000 deaths annually and 500,000 new cases per annum. Persistent infection with one or more carcinogenic types of human papillomavirus (HPV) is an important etiologic factor in the development of cervical intraepithelial neoplasia and the progression to cervical cancer. HPV DNA has been detected in up to 99.7% of invasive cervical cancers worldwide.The carcinogenic effect of the "high-risk" HPVs, as defined by their documented association with invasive carcinomas, is thought to be mediated by two viral oncoprotein, E6 and E7, through their action of inactivating the function of two important cellular tumor suppressor, p53 and pRb. It has been demonstrated that the E6 oncoprotein interacts with p53 to promote its degradation, whereas the E7 oncoprotein form complex with Rb, leading to its functional inactivation as well as accelerated degradation. These synergistic effects result in a deregulated cell cycle control and are thus believed to be critically important in HPV-induced carcinogene, 172406, Microbiology, 226688, Biology, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books

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ISBN: 9783659281051

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Cervical cancer is one of the most frequent diseases in women,it is comprises approximately 12% of all cancer in women worldwide and the second most common type, after breast cancer, with about 200,000 deaths annually and 500,000 new cases per annum. Persistent infection with one or more carcinogenic types of human papillomavirus (HPV) is an important etiologic factor in the development of cervical intraepithelial neoplasia and the progression to cervical cancer. HPV DNA has been detected in up to 99.7% of invasive cervical cancers worldwide.The carcinogenic effect of the ´´high-risk´´ HPVs, as defined by their documented association with invasive carcinomas, is thought to be mediated by two viral oncoprotein, E6 and E7, through their action of inactivating the function of two important cellular tumor suppressor, p53 and pRb. It has been demonstrated that the E6 oncoprotein interacts with p53 to promote its degradation, whereas the E7 oncoprotein form complex with Rb, leading to its functional inactivation as well as accelerated degradation. These synergistic effects result in a deregulated cell cycle control and are thus believed to be critically important in HPV-induced carcinogene A Study on Human Papillomavirus: High-Risk E6, p53 and p16 Proteins Expression and Their Role in Cervical Carcinogenesis Buch (dtsch.) Bücher>Fremdsprachige Bücher>Englische Bücher, LAP Lambert Academic Publishing

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High-Risk Human Papillomavirus and Cervical Carcinoma: A Study on Human Papillomavirus: High-Risk E6, p53 and p16 Proteins Expression and Their Role in Cervical Carcinogenesis - Arwa Al-Shuwaikh
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Arwa Al-Shuwaikh:
High-Risk Human Papillomavirus and Cervical Carcinoma: A Study on Human Papillomavirus: High-Risk E6, p53 and p16 Proteins Expression and Their Role in Cervical Carcinogenesis - Taschenbuch

2013, ISBN: 3659281050

Taschenbuch, [EAN: 9783659281051], LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Book, [PU: LAP LAMBERT Academic Publishing], 2013-03-22, LAP LAMBERT Academic Publishing, 56491011, Mikrobiologie, 56458011, Biowissenschaften, 56047011, Wissenschaft, 54071011, Genres, 52044011, Fremdsprachige Bücher

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High-Risk Human Papillomavirus and Cervical Carcinoma - Al-Shuwaikh Arwa
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Al-Shuwaikh Arwa:
High-Risk Human Papillomavirus and Cervical Carcinoma - Taschenbuch

2013, ISBN: 3659281050

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High-Risk Human Papillomavirus and Cervical Carcinoma
Autor:

Al-Shuwaikh Arwa

Titel:
ISBN-Nummer:

Cervical cancer is one of the most frequent diseases in women,it is comprises approximately 12% of all cancer in women worldwide and the second most common type, after breast cancer, with about 200,000 deaths annually and 500,000 new cases per annum. Persistent infection with one or more carcinogenic types of human papillomavirus (HPV) is an important etiologic factor in the development of cervical intraepithelial neoplasia and the progression to cervical cancer. HPV DNA has been detected in up to 99.7% of invasive cervical cancers worldwide.The carcinogenic effect of the "high-risk" HPVs, as defined by their documented association with invasive carcinomas, is thought to be mediated by two viral oncoprotein, E6 and E7, through their action of inactivating the function of two important cellular tumor suppressor, p53 and pRb. It has been demonstrated that the E6 oncoprotein interacts with p53 to promote its degradation, whereas the E7 oncoprotein form complex with Rb, leading to its functional inactivation as well as accelerated degradation. These synergistic effects result in a deregulated cell cycle control and are thus believed to be critically important in HPV-induced carcinogene

Detailangaben zum Buch - High-Risk Human Papillomavirus and Cervical Carcinoma


EAN (ISBN-13): 9783659281051
ISBN (ISBN-10): 3659281050
Taschenbuch
Erscheinungsjahr: 2013
Herausgeber: AV Akademikerverlag GmbH & Co. KG.

Buch in der Datenbank seit 10.10.2014 09:29:12
Buch zuletzt gefunden am 30.09.2017 20:47:52
ISBN/EAN: 9783659281051

ISBN - alternative Schreibweisen:
3-659-28105-0, 978-3-659-28105-1


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