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Analytical Methods for Determination of Electrophilic Intermediates - Catrina Dupard-Julien
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
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Catrina Dupard-Julien:
Analytical Methods for Determination of Electrophilic Intermediates - neues Buch

ISBN: 9783659713279

ID: 06b382c1fa1a72aaf28002399d251d17

In view of the reactive properties of Electrophilic intermediates (EIs) and their involvement in various disease processes (cancer, diabetes, and drug-sensitivity), their quantitative determination is very important. This book is directed towards the development of methods for the determination of epoxides, , -unsaturated carbonyls and , -dicarbonyls. 1,2-Epoxy-3-butene (EB), methyl vinyl ketone (MVK), and alloxan were used as representative molecules. Following derivatization with N,N-diethyldithiocarbamate (DTC) or 1,2-phenylenediamine (PD), the stable adducts of EIs were analyzed by reversed phase (RP) high-performance liquid chromatography (HPLC) coupled with either UV or fluorescence detection. This facilitated the detection of all three compounds, viz., EB, MVK and alloxan. The detection and reproducibility were accomplished to lower picomole or femtomole levels. Further, this approach was robust and easily adaptable for the analysis of various EIs belonging to the above class of compounds. The methods were suitable for analysis of EI's in biological fluids viz., fetal bovine serum and tissue homogenates of brain, heart, liver and kidney. Bücher / Naturwissenschaften, Medizin, Informatik & Technik / Chemie

Neues Buch Dodax.de
Nr. 57bda3975a87230916f6fc38 Versandkosten:Versandkosten: 0.0 EUR, Lieferzeit: 6 Tage, DE. (EUR 0.00)
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Analytical Methods for Determination of Electrophilic Intermediates - Dupard-Julien, Catrina
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Dupard-Julien, Catrina:
Analytical Methods for Determination of Electrophilic Intermediates - gebunden oder broschiert

ISBN: 9783659713279

ID: 883644a355865caab0141799212b7b2d

In view of the reactive properties of Electrophilic intermediates (EIs) and their involvement in various disease processes (cancer, diabetes, and drug-sensitivity), their quantitative determination is very important. This book is directed towards the development of methods for the determination of epoxides, a,ß-unsaturated carbonyls and a,ß-dicarbonyls. 1,2-Epoxy-3-butene (EB), methyl vinyl ketone (MVK), and alloxan were used as representative molecules. Following derivatization with N,N-diethyldithiocarbamate (DTC) or 1,2-phenylenediamine (PD), the stable adducts of EIs were analyzed by reversed phase (RP) high-performance liquid chromatography (HPLC) coupled with either UV or fluorescence detection. This facilitated the detection of all three compounds, viz., EB, MVK and alloxan. The detection and reproducibility were accomplished to lower picomole or femtomole levels. Further, this approach was robust and easily adaptable for the analysis of various EIs belonging to the above class of compounds. The methods were suitable for analysis of EI's in biological fluids viz., fetal bovine serum and tissue homogenates of brain, heart, liver and kidney. Buch / Mathematik, Naturwissenschaft & Technik / Chemie / Populäre Darstellungen

Neues Buch Buecher.de
Nr. 43142257 Versandkosten:, , DE. (EUR 0.00)
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(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.
Analytical Methods for Determination of Electrophilic Intermediates - Dupard-Julien, Catrina
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
(*)
Dupard-Julien, Catrina:
Analytical Methods for Determination of Electrophilic Intermediates - gebunden oder broschiert

ISBN: 9783659713279

ID: 883644a355865caab0141799212b7b2d

In view of the reactive properties of Electrophilic intermediates (EIs) and their involvement in various disease processes (cancer, diabetes, and drug-sensitivity), their quantitative determination is very important. This book is directed towards the development of methods for the determination of epoxides, , -unsaturated carbonyls and , -dicarbonyls. 1,2-Epoxy-3-butene (EB), methyl vinyl ketone (MVK), and alloxan were used as representative molecules. Following derivatization with N,N-diethyldithiocarbamate (DTC) or 1,2-phenylenediamine (PD), the stable adducts of EIs were analyzed by reversed phase (RP) high-performance liquid chromatography (HPLC) coupled with either UV or fluorescence detection. This facilitated the detection of all three compounds, viz., EB, MVK and alloxan. The detection and reproducibility were accomplished to lower picomole or femtomole levels. Further, this approach was robust and easily adaptable for the analysis of various EIs belonging to the above class of compounds. The methods were suitable for analysis of EI's in biological fluids viz., fetal bovine serum and tissue homogenates of brain, heart, liver and kidney. Buch / Mathematik, Naturwissenschaft & Technik / Chemie

Neues Buch Buecher.de
Nr. 43142257 Versandkosten:, , DE. (EUR 0.00)
Details...
(*) Derzeit vergriffen bedeutet, dass dieser Titel momentan auf keiner der angeschlossenen Plattform verfügbar ist.