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Intracranial Germ Cell Tumors - Sawamura, Yutaka / Shirato, Hiroki
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
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Sawamura, Yutaka / Shirato, Hiroki:
Intracranial Germ Cell Tumors - neues Buch

ISBN: 3709174147

ID: 20063329548

[EAN: 9783709174142], Neubuch, Publisher/Verlag: Springer, Wien | Intracranial germ cell tumors are a group of uncommon neoplasms of the central nervous system. The clinical features and natural history of these lesions are quite unique and variable. While intracranial germ cell tumors have been a fascination to neurooncologists for decades, the relatively small number of patients seen in any single institution has hampered the important clinical investigation that is so needed.This text is complete with detailed information concerning the epidemiology, pathology, oncological biology, clinical findings, radiology, and treatment options including surgical strategy, radiotherapy, and chemotherapy for this heterogeneous group of neoplasms. The ongoing clinical trials concerning the optimization of therapy are efficiently summarized. An important final segment addresses the late sequelae of therapy which is of great significance since the majority suffering from these tumors are young patients.This first and only book on intracranial germ cell tumors includes excellent and comprehensive data sheets, illustrations, and radiograms. It provides a detailed and outstanding reference source for physicians taking care of patients with intracranial germ cell tumors, and will be a very welcome edition to their reference libraries. | I. Introduction.- II. WHO histological classification of tumors of the central nervous system (CNS): germ cell tumors (GCTs).- III. Epidemiology of CNS GCTs.- 1. Histological variation and incidence.- 2. Racial and geographical factors.- 3. Age factor.- 4. Gender factor.- 5. Anatomical factor.- 6. Genetic factor.- 7. Other factors.- IV. Pathology.- 1. General features of GCTs.- 2. Germinoma.- 3. Embryonal carcinoma.- 4. Yolk sac tumor (Endodermal sinus tumor).- 5. Choriocarcinoma.- 6. Teratomas.- 6.1 Mature teratoma.- 6.2 Immature teratoma.- 6.3 Teratoma with malignant elements.- V. Immunobiology of tumor infiltrating lymphocytes (TIL) in germinomas.- 1. Cell types of germinoma TIL.- 2. The cause and role of immune cell infiltration in germinomas.- 3. Cytotoxicity of TIL to tumor cells.- 4. Conclusive remarks.- VI. Genesis and genetics of intracranial germ cell tumors.- 1. Clonal evolution model for tumorigenesis.- 2. Oncogenes and tumor suppressor genes.- 3. Problematic of ontogenesis of CNS and extracranial GCTs.- 3.1 All cells originate from primordial germ cells.- 3.2 All cells originate from different precursors during early embryonic development.- 3.3 Primordial germ cells have a physiological role outside the gonads.- 3.4 All cells originate from early toti- or pluri-potent precursor cells.- 4. Oncogenesis of GCTs.- 4.1 Oncogenesis of extracranial GCTs.- 4.2 Oncogenesis of CNS GCTs.- 4.2.1 Cytogenetic findings.- 4.2.2 Genomic studies.- VII. Clinical findings and diagnosis.- 1. Neurological manifestations.- 1.1 Neurological signs and symptoms.- 1.2 Disturbances of vertical eye movements.- 1.2.1 Posterior commissure.- 1.2.2 Rostral interstitial nucleus of the medial longitudinal fasciculus (riMLF).- 1.2.3 Interstitial nucleus of Cajal and periaqueductal gray matter.- 1.3 Signs and symptoms of the tumors in unusual sites.- Radiological diagnosis.- 2.1 Overview of the imaging of brain tumors.- 2.2 Imaging of CNS GCTs.- 2.2.1 Germinomas.- 2.2.2 Teratomas.- 2.2.3 Choriocarcinoma.- 2.2.4 Yolk sac tumor (Endodermal sinus tumor).- 2.2.5 Embryonal carcinoma.- 2.2.6 Mixed GCTs.- 2.3 Differential diagnosis.- 2.3.1 Pineal region.- 2.3.2 Sellar and suprasellar region.- 2.3.3 Basal ganglia and thalamus.- 3. Endocrinological manifestations.- 3.1 Diabetes insipidus.- 3.2 Anterior pituitary hormone deficits.- 3.3 Endocrine evaluation.- 3.4 Precocious puberty.- 4. Ophthalmological manifestations.- 4.1 Visual symptoms caused by suprasellar GCTs.- 4.2 Visual field defects caused by germinoma.- 4.3 Prognosis of visual disturbance.- 5. Tumor markers.- 5.1 Alpha-fetoprotein.- 5.2 Human chorionic gonadotropin.- 5.3 Human placental alkaline phosphatase.- 5.4 C

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Intracranial Germ Cell Tumors - Herausgegeben von Sawamura, Yutaka Shirato, Hiroki Tribolet, Nicolas de
Vergriffenes Buch, derzeit bei uns nicht verfügbar.
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Herausgegeben von Sawamura, Yutaka Shirato, Hiroki Tribolet, Nicolas de:
Intracranial Germ Cell Tumors - Taschenbuch

2011, ISBN: 9783709174142

[ED: Softcover], [PU: Springer, Wien Springer, Berlin], Intracranial germ cell tumors are a group of uncommon neoplasms of the central nervous system. The clinical features and natural history of these lesions are quite unique and variable. While intracranial germ cell tumors have been a fascination to neurooncologists for decades, the relatively small number of patients seen in any single institution has hampered the important clinical investigation that is so needed. This text is complete with detailed information concerning the epidemiology, pathology, oncological biology, clinical findings, radiology, and treatment options including surgical strategy, radiotherapy, and chemotherapy for this heterogeneous group of neoplasms. The ongoing clinical trials concerning the optimization of therapy are efficiently summarized. An important final segment addresses the late sequelae of therapy which is of great significance since the majority suffering from these tumors are young patients. This first and only book on intracranial germ cell tumors includes excellent and comprehensive data sheets, illustrations, and radiograms. It provides a detailed and outstanding reference source for physicians taking care of patients with intracranial germ cell tumors, and will be a very welcome edition to their reference libraries. Softcover reprint of the original 1st ed. 1998. 2011. xiv, 369 S. XIV, 369 pp. 111 partly coloured figs Sofort lieferbar, [SC: 0.00], Neuware, gewerbliches Angebot

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Intracranial Germ Cell Tumors - Yukata Sawamura
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Yukata Sawamura:
Intracranial Germ Cell Tumors - neues Buch

2011, ISBN: 3709174147

ID: 17180189107

[EAN: 9783709174142], Nieuw boek, [SC: 11.14], [PU: Springer Verlag GmbH], New Book. Shipped from US within 10 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

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Intracranial Germ Cell Tumors - Yutaka Sawamura; Hiroki Shirato; Nicolas de Tribolet
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Yutaka Sawamura; Hiroki Shirato; Nicolas de Tribolet:
Intracranial Germ Cell Tumors - Taschenbuch

2011, ISBN: 9783709174142

ID: 27911980

Softcover reprint of the original 1st ed. 1998, Softcover, Buch, [PU: Springer Wien]

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Intracranial Germ Cell Tumors - Yukata Sawamura
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Yukata Sawamura:
Intracranial Germ Cell Tumors - Taschenbuch

ISBN: 9783709174142

Paperback, [PU: SPRINGER VERLAG GMBH], Oncology

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Intracranial Germ Cell Tumors
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Herausgegeben von Sawamura, Yutaka Shirato, Hiroki Tribolet, Nicolas de

Titel:

Intracranial Germ Cell Tumors

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Detailangaben zum Buch - Intracranial Germ Cell Tumors


EAN (ISBN-13): 9783709174142
ISBN (ISBN-10): 3709174147
Taschenbuch
Erscheinungsjahr: 2011
Herausgeber: Springer Vienna

Buch in der Datenbank seit 17.12.2013 22:07:57
Buch zuletzt gefunden am 14.02.2017 17:45:10
ISBN/EAN: 9783709174142

ISBN - alternative Schreibweisen:
3-7091-7414-7, 978-3-7091-7414-2


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