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Development of Novel Peptide Inhibitors to Bag-1 - Brunn Jonathan
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Brunn Jonathan:
Development of Novel Peptide Inhibitors to Bag-1 - neues Buch

2014, ISBN: 9783846543023

ID: 9783846543023

Development of Novel Peptide Inhibitors to Bag-1: Paperback: LAP Lambert Academic Publishing: 9783846543023: 26 Feb 2014: One of the most challenging aspects of treating tumors with chemotherapy is that the tumors can develop a resistance to the chemotherapy and survive while the rest of the healthy, non-cancerous cells perish. Higher doses of chemotherapy deliver fewer positive results and at the expense of greater side effects. The purpose of this book it to identify and exploit a. One of the most challenging aspects of treating tumors with chemotherapy is that the tumors can develop a resistance to the chemotherapy and survive while the rest of the healthy, non-cancerous cells perish. Higher doses of chemotherapy deliver fewer positive results and at the expense of greater side effects. The purpose of this book it to identify and exploit a weakness at the molecular level of the anti-apoptotic pathway utilized by cancer cells to turn off the "triggered cell death" mechanism of apoptosis and survive chemotherapy. We specifically target the interaction between the anti-apoptotic protein Bcl-2 Associated Athanogene (BAG-1) and the 70-kilodalton Heat Shock Protein (HSP-70) that is suspected of driving the chemotherapeutic resistance, and seek to disrupt that interaction via peptidyl-biomimetically engineered peptides that are predicted via an in-house computational software named 'Contact" and experimentally verified via Biacore (c) binding assays. Biochemistry, , , , Development of Novel Peptide Inhibitors to Bag-1, Brunn Jonathan, 9783846543023, LAP Lambert Academic Publishing, , , , ,

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Development of Novel Peptide Inhibitors to BAG1 - Jonathan Brunn
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Jonathan Brunn:
Development of Novel Peptide Inhibitors to BAG1 - neues Buch

2014, ISBN: 9783846543023

[PU: LAP Lambert Academic Publishing], Das BuchDevelopment of Novel Peptide Inhibitors to BAG1könnte eine längere Lieferzeit habenSie zahlen eine Versandpauschale für bis zu fünf Bücher Typ:book One of the most challenging aspects of treating tumors with chemotherapy is that the tumors can develop a resistance to the chemotherapy and survive while the rest of the healthy noncancerous cells perish Higher doses of chemotherapy deliver fewer positive results and at the expense of greater side effects The purpose of this book it to identify and exploit a weakness at the molecular level of the antiapoptotic pathway utilized by cancer cells to turn off the triggered cell death mechanism of apoptosis and survive chemotherapy We specifically target the interaction between the antiapoptotic protein Bcl2 Associated Athanogene (BAG1) and the 70kilodalton Heat Shock Protein (HSP70) that is suspected of driving the chemotherapeutic resistance and seek to disrupt that interaction via peptidylbiomimetically engineered peptides that are predicted via an inhouse computational software named 'Contact and experimentally verified via Biacore (c) binding assays, [SC: 0.00], Neuware, gewerbliches Angebot, [GW: 1410g]

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Development of Novel Peptide Inhibitors to Bag-1 - Brunn Jonathan
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Brunn Jonathan:
Development of Novel Peptide Inhibitors to Bag-1 - neues Buch

ISBN: 9783846543023

Brunn Jonathan,Paperback, English-language edition,Pub by AV Akademikerverlag GmbH & Co. KG. Books Books ~~ Science~~ Life Sciences ~~ Biochemistry Development-of-Novel-Peptide-Inhibitors-to-BAG-1~~Brunn-Jonathan AV Akademikerverlag GmbH & Co. KG.

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Development of Novel Peptide Inhibitors to Bag-1 - Brunn Jonathan
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Brunn Jonathan:
Development of Novel Peptide Inhibitors to Bag-1 - Taschenbuch

ISBN: 9783846543023

ID: 9783846543023

Development of Novel Peptide Inhibitors to Bag-1 Development-of-Novel-Peptide-Inhibitors-to-BAG-1~~Brunn-Jonathan Science/Tech>Biology>Biology Paperback, AV Akademikerverlag GmbH & Co. KG.

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Development of Novel Peptide Inhibitors to BAG-1 - Jonathan Brunn
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Jonathan Brunn:
Development of Novel Peptide Inhibitors to BAG-1 - Taschenbuch

2014, ISBN: 9783846543023

ID: 29309192

Applications of Peptidyl-Biomimetics to reduce and eliminate tumor resistance to chemotherapy, Softcover, Buch, [PU: LAP Lambert Academic Publishing]

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