Linking dynamics of ion channels with biological function - neues Buch
ISBN: 9783838150956
Ion channels are membrane proteins, regulating biological processes by controlling passive ion flux across cell membranes. With more than 60 ion channel diseases identified to date, ion c… Mehr…
Ion channels are membrane proteins, regulating biological processes by controlling passive ion flux across cell membranes. With more than 60 ion channel diseases identified to date, ion channels have great potential for the treatment of disease. Several drugs that modulate ion channels are in clinical use. Owing to the complexity of these channels and the lack of 3D structures, rational drug design is challenging. For most ion channels no specific ligands have been identified. Another complicating factor for drug development arises from the fact that ion channels undergo conformational changes during gating, leading to different binding affinities and changes in binding site accessibilities. Thus, a better understanding of the structure, gating dynamics and molecular mechanisms underlying disease is urgently needed. My research addresses several of these fundamental questions including methods to develop accurate and reliable 3D structure models, investigations of gating mechanisms and analyses of drug receptor interactions. Bücher / Naturwissenschaften, Medizin, Informatik & Technik / Naturwissenschaften allgemein<
Linking dynamics of ion channels with biological function - neues Buch
ISBN: 9783838150956
Ion channels are membrane proteins, regulating biological processes by controlling passive ion flux across cell membranes. With more than 60 ion channel diseases identified to date, ion c… Mehr…
Ion channels are membrane proteins, regulating biological processes by controlling passive ion flux across cell membranes. With more than 60 ion channel diseases identified to date, ion channels have great potential for the treatment of disease. Several drugs that modulate ion channels are in clinical use. Owing to the complexity of these channels and the lack of 3D structures, rational drug design is challenging. For most ion channels no specific ligands have been identified. Another complicating factor for drug development arises from the fact that ion channels undergo conformational changes during gating, leading to different binding affinities and changes in binding site accessibilities. Thus, a better understanding of the structure, gating dynamics and molecular mechanisms underlying disease is urgently needed. My research addresses several of these fundamental questions including methods to develop accurate and reliable 3D structure models, investigations of gating mechanisms and analyses of drug receptor interactions. Bücher, Hörbücher & Kalender / Bücher / Sachbuch / Naturwissenschaften<
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Linking dynamics of ion channels with biological function - neues Buch
ISBN: 9783838150956
Ion channels are membrane proteins, regulating biological processes by controlling passive ion flux across cell membranes. With more than 60 ion channel diseases identified to date, ion c… Mehr…
Ion channels are membrane proteins, regulating biological processes by controlling passive ion flux across cell membranes. With more than 60 ion channel diseases identified to date, ion channels have great potential for the treatment of disease. Several drugs that modulate ion channels are in clinical use. Owing to the complexity of these channels and the lack of 3D structures, rational drug design is challenging. For most ion channels no specific ligands have been identified. Another complicating factor for drug development arises from the fact that ion channels undergo conformational changes during gating, leading to different binding affinities and changes in binding site accessibilities. Thus, a better understanding of the structure, gating dynamics and molecular mechanisms underlying disease is urgently needed. My research addresses several of these fundamental questions including methods to develop accurate and reliable 3D structure models, investigations of gating mechanisms and analyses of drug receptor interactions. Bücher / Naturwissenschaften, Medizin, Informatik & Technik / Naturwissenschaften allgemein<
Linking dynamics of ion channels with biological function - neues Buch
ISBN: 9783838150956
Ion channels are membrane proteins, regulating biological processes by controlling passive ion flux across cell membranes. With more than 60 ion channel diseases identified to date, ion c… Mehr…
Ion channels are membrane proteins, regulating biological processes by controlling passive ion flux across cell membranes. With more than 60 ion channel diseases identified to date, ion channels have great potential for the treatment of disease. Several drugs that modulate ion channels are in clinical use. Owing to the complexity of these channels and the lack of 3D structures, rational drug design is challenging. For most ion channels no specific ligands have been identified. Another complicating factor for drug development arises from the fact that ion channels undergo conformational changes during gating, leading to different binding affinities and changes in binding site accessibilities. Thus, a better understanding of the structure, gating dynamics and molecular mechanisms underlying disease is urgently needed. My research addresses several of these fundamental questions including methods to develop accurate and reliable 3D structure models, investigations of gating mechanisms and analyses of drug receptor interactions. Bücher, Hörbücher & Kalender / Bücher / Sachbuch / Naturwissenschaften<
Nr. 4VHT8AJH2VB. Versandkosten:, Lieferzeit: 5 Tage, DE. (EUR 0.00)
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Ion channels are membrane proteins, regulating biological processes by controlling passive ion flux....
Detailangaben zum Buch - Linking dynamics of ion channels with biological function
EAN (ISBN-13): 9783838150956 ISBN (ISBN-10): 3838150953 Taschenbuch Erscheinungsjahr: 2015 Herausgeber: Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG Nov 2015
Buch in der Datenbank seit 2016-10-08T02:17:22+02:00 (Berlin) Detailseite zuletzt geändert am 2020-11-30T20:15:39+01:00 (Berlin) ISBN/EAN: 9783838150956
ISBN - alternative Schreibweisen: 3-8381-5095-3, 978-3-8381-5095-6 Alternative Schreibweisen und verwandte Suchbegriffe: Autor des Buches: anna Titel des Buches: dynamics, ion
